Generation of tricyclic imidazo[1,2-a]pyrazines as novel PI3K inhibitors by application of a conformational restriction strategy

Generation of tricyclic imidazo[1,2-a]pyrazines as novel PI3K inhibitors by application of a conformational restriction strategy

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 27, Issue 11, 1 June 2017, Pages 2536-2543

Sonia Martínez González, Sonsoles Rodríguez-Arístegui, Ana Isabel Hernández, Carmen Varela, Esther González Cantalapiedra, Rosa María Álvarez, Antonio Rodríguez Hergueta, James R. Bischoff, María Isabel Albarrán, Antonio Cebriá,