Synthesis and in vitro evaluation of SG3227, a pyrrolobenzodiazepine dimer antibody-drug conjugate payload based on sibiromycin

Synthesis and in vitro evaluation of SG3227, a pyrrolobenzodiazepine dimer antibody-drug conjugate payload based on sibiromycin

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 27, Issue 5, 1 March 2017, Pages 1154-1158

Gary C. Kemp, Arnaud C. Tiberghien, Neki V. Patel, Francois D'Hooge, Sanjay M. Nilapwar, Lauren R. Adams, Simon Corbett, David G. Williams, John A. Hartley, Philip W. Howard,