Discovery of a 2′-fluoro-2′-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties

Discovery of a 2′-fluoro-2′-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 27, Issue 8, 15 April 2017, Pages 1840-1847

Thorsten A. Kirschberg, Sammy Metobo, Michael O. Clarke, Vangelis Aktoudianakis, Darius Babusis, Ona Barauskas, Gabriel Birkus, Thomas Butler, Daniel Byun, Gregory Chin, Edward Doerffler, Thomas E. Edwards, Martijn Fenaux, Rick Lee, Willard Lew,