Selectivity switch between FAK and Pyk2: Macrocyclization of FAK inhibitors improves Pyk2 potency

Selectivity switch between FAK and Pyk2: Macrocyclization of FAK inhibitors improves Pyk2 potency

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 26, Issue 24, 15 December 2016, Pages 5926-5930

Julie Farand, Nicholas Mai, Jayaraman Chandrasekhar, Zachary E. Newby, Josh Van Veldhuizen, Jennifer Loyer-Drew, Chandrasekar Venkataramani, Juan Guerrero, Amy Kwok, Ning Li, Yelena Zherebina, Sibylle Wilbert, Jeff Zablocki, Gary Phillips,