Synthesis of novel trifluoromethyl-substituted spiro-[chromeno[4,3-d]pyrimidine-5,1′-cycloalkanes], and evaluation of their analgesic effects in a mouse pain model

Synthesis of novel trifluoromethyl-substituted spiro-[chromeno[4,3-d]pyrimidine-5,1′-cycloalkanes], and evaluation of their analgesic effects in a mouse pain model

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 27, Issue 7, 1 April 2017, Pages 1551-1556

Helio G. Bonacorso, Wilian C. Rosa, Sara M. Oliveira, Indiara Brusco, Evelyne S. Brum, Melissa B. Rodrigues, Clarissa P. Frizzo, Nilo Zanatta,