Discovery of highly potent and selective orexin 1 receptor antagonists (1-SORAs) suitable for in vivo interrogation of orexin 1 receptor pharmacology

Discovery of highly potent and selective orexin 1 receptor antagonists (1-SORAs) suitable for in vivo interrogation of orexin 1 receptor pharmacology

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 26, Issue 23, 1 December 2016, Pages 5809-5814

Craig A. Stump, Andrew J. Cooke, Joseph Bruno, Tamara D. Cabalu, Anthony L. Gotter, C. Meacham Harell, Scott D. Kuduk, Terrence P. McDonald, Julie O'Brien, John J. Renger, Peter D. Williams, Christopher J. Winrow, Paul J. Coleman,