کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
51581 | 46847 | 2011 | 4 صفحه PDF | دانلود رایگان |
A new type of phosphate-pyridine (P, N) ligand derived from d-glucosamine and BINOL was synthesized and successfully applied in Cu-catalyzed enantioselective conjugate addition of diethylzinc to chalcones for the first time, high yields and enantioselectivities were obtained when the ligand 10a which contains (S)-BINOL was used. The results also showed that the configuration of BINOL at the ligand backbone had remarkable effects on the activities and enantioselectivities.
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► A new type of P,N ligand which derived from D-glucosamine was synthesized.
► It has been successfully used in asymmetric 1,4-conjugate addition reactions.
► The configuration of BINOL at the ligand have effect on the reaction was proved.
Journal: Catalysis Communications - Volume 16, Issue 1, 30 November 2011, Pages 155–158