Synthesis of HgS nanocrystals in the Lysozyme aqueous solution through biomimetic method

► HgS nanocrystals were prepared in Lysozyme solutions by biomimetic method. ► HgS nanocrystals exhibited good luminescence properties. ► Investigation on interaction of Hg2+/HgS nanocrystals and Lysozyme. ► The change of secondary structure of Lysozyme due to binding to HgS nanocrystals.