Biocompatible polymeric implants for controlled drug delivery produced by MAPLE

► Implants consisting of indomethacin coated with polymeric films were produced by MAPLE. ► The implants were tested in vitro in conditions close to those encountered inside the body. ► The implants containing PEG:PLGA films exhibit enhanced biocompatibility. ► The implants containing PEG:PLGA films offer prolonged release rates of the drug. ► The drug release is controlled by a diffusion mediated mechanism (Higuchi's model).