Remarkable difference in catalytic performance of an organoamino-functionalized MCM-41-HPA composite with controlled site-isolation and site-aggregation

► Novel organoamino-functionalized MCM-41 silicas are successfully prepared. ► Different distribution patterns-site-isolation or site-aggregation was obtained. ► The solvents have remarkable effect on the loading and distribution of organic moieties. ► H3PW12O40 was successfully loaded on the NH2-functionalized MCM-41. ► Distinct performances in the catalytic oxidation of cycloocta-1,5-diene were obtained.