کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5376162 | 1504313 | 2008 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A neutron crystallographic analysis of a cubic porcine insulin at pD 6.6
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی تئوریک و عملی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
In the case of HisB5, both NÏ and NÏ of an imidazole ring are protonated at pD 6.6, but at pD 9 only NÏ is protonated. In contrast, for HisB10, both NÏ and NÏ are protonated at pD 6.6 as well as at pD 9. The ionization states of several amino acids in porcine insulin have been obtained at pD 6.6 and they are compared with those at pD 9 obtained by neutron diffraction as well as those at pH 6.50 and 6.98 obtained by X-ray diffraction. In this manuscript, the difference between these forms will be discussed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chemical Physics - Volume 345, Issues 2â3, 18 April 2008, Pages 152-158
Journal: Chemical Physics - Volume 345, Issues 2â3, 18 April 2008, Pages 152-158
نویسندگان
Takuya Ishikawa, Toshiyuki Chatake, Yuki Ohnishi, Ichiro Tanaka, Kazuo Kurihara, Ryota Kuroki, Nobuo Niimura,