Magnetic resonance Spectroscopy with Linear Algebraic Modeling (SLAM) for higher speed and sensitivity

► SLAM is a new method of localizing spectra to C anatomic compartments located by MRI. ► C phase-encoding gradients are selected from central k-space to maximize SNR. ► Compartment-average spectra are reconstructed from a reduced CSI equation set. ► Application to 24 31P heart MRS studies yields same quantitative results 4-times faster. ► Proactive application in 6 hearts yields 30-40% 31P MRS SNR gain in same time and volume.