Swift Acetate Glial Assay (SAGA): An accelerated human 13C MRS brain exam for clinical diagnostic use

► 13C acetate MR spectroscopy defines glial metabolic rate for human brain. ► Low power 13C- noise decoupling metabolic rate determinations in frontal brain. ► Accelerated determination of human brain metabolism with 13C MRS in 25.6 min (SAGA). ► 13C acetate glial metabolic rate equivalent to measurements by conventional methods.