کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5407423 1393216 2007 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The effects of SNR on ADC measurements in diffusion-weighted hyperpolarized He-3 MRI
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی تئوریک و عملی
پیش نمایش صفحه اول مقاله
The effects of SNR on ADC measurements in diffusion-weighted hyperpolarized He-3 MRI
چکیده انگلیسی
The theoretical dependence of the mean and standard deviation of ADC values on signal-to-noise ratio (SNR) was derived and compared to measured values in porous phantoms and the lungs of human subjects using diffusion-weighted hyperpolarized helium-3 MRI. For SNR values below 15, mean ADC values were highly SNR-dependent due to a combination of noise and choice of noise thresholding. Above SNR values of 15 and for mean ADC values within ranges relevant for evaluating lung disease (<0.6 cm2/s), the mean ADC was largely independent of SNR. The standard deviation, by contrast, was highly dependent on SNR over a much larger range, but this dependence was well predicted by theory, suggesting the histogram of ADC values might be corrected for these stochastic processes to more accurately evaluate disease using restricted diffusion measures in the lungs.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Magnetic Resonance - Volume 185, Issue 1, March 2007, Pages 42-49
نویسندگان
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