کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5462802 1517179 2017 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis and drug delivery property of silica nanotubes prepared using gelatin nanofibers as novel sacrificed template
ترجمه فارسی عنوان
سنتز و ویژگی تحویل دارو از نانولوله های سیلیکا با استفاده از نانو فیبر ژلاتین به عنوان قالب جدید فداکار
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه مهندسی مواد فناوری نانو (نانو تکنولوژی)
چکیده انگلیسی
Silica nanotubes were prepared using the gelatin nanofibers as novel sacrificed template via a sol-gel route with a subsequent calcination process. FT-IR spectrum showed that the siloxane bonds (Si-O-Si) were involved in the silica nanotubes. SEM observations showed that the silica nanotubes had an average diameter of 742 ± 82 nm with a hollow cavity of 513 ± 68 nm. The formation of the tubular hollow structure was attributed to the removal of gelatin template. After soaked in the solution of tetracycline hydrochloride (TH, one of the representative antibiotics) as model drug, the silica nanotubes favored the adsorption of TH with the loading efficiency of 38%. A sustained release behavior of TH was observed as the TH-loaded silica nanotubes were soaked in the phosphate buffer saline. The released TH was biologically active to strongly inhibit the growth of bacterial E. coli.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Letters - Volume 209, 15 December 2017, Pages 334-337
نویسندگان
, , , , , ,