BNCT of skin tumors using the high-energy D-T neutrons

A typical simulated phantom, subjected to the irradiation of the designed spectrum, is used to study the performance of the resultant beam in shallow tissue. For an arbitrary chosen 10B concentration, the evaluated depth-dose curves show that the proposed configuration establishes acceptable agreement between the appropriate neutron intensity and penetration to desired depth in tissue in a reasonable treatment time of about 25-38 min. Considering the simulations carried out, the total dose delivered to the tumor is expected to be of about 4.2 times higher than that delivered to the first depths in healthy tissue, and of about 2.4 times higher than that delivered to the normal skin. These results in essence endorse the ability of D-T neutron generators to be used for BNCT of surface tumors, even with the yield of ∼1012 n/s.