کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5503228 1535087 2017 31 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Reliability of single- and paired-pulse transcranial magnetic stimulation for the assessment of knee extensor muscle function
ترجمه فارسی عنوان
قابلیت اطمینان از تحریک مغناطیسی مغز و اعصاب مغز و نخاع برای ارزیابی عملکرد عضلات انقباض زانو
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
چکیده انگلیسی
This study examined inter-session and intra-session transcranial magnetic stimulation (TMS) reliability at two test stimulus intensities in the knee extensors. Strong and weak TMS was delivered via single- and paired- (3-ms and 100-ms inter-stimulus interval) pulses on the same day and different days. All stimuli were delivered during isometric contractions of the knee extensors at 20% of maximal voluntary force. Motor-evoked potentials (MEP) were assessed in quadriceps femoris muscles. Relative (intra-class correlation coefficient, ICC) and absolute (standard error of measurement, SEM) reliability and variability (coefficient of variation) were assessed. MEPs elicited by strong and weak single-pulse TMS had excellent relative reliability in all muscles as did weak short-interval and strong long-interval paired-pulse TMS (all ICC > 0.75). Conversely, relative reliability of strong short-interval and weak long-interval paired-pulse TMS was lower (ICC: 0.34-0.83 and 0.22-0.97, respectively). MEP size variability was lower (P < 0.05) and SEM comparable or lower in strong compared to weak TMS conditions. These results suggest single- and paired-pulse TMS at both strong and weak intensities are generally reliable in the knee extensors. Strong (or both strong and weak) single-pulse TMS is recommended. The results indicate using weak test pulses for short-interval and strong test pulses for long-interval paired-pulse TMS are recommended.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the Neurological Sciences - Volume 375, 15 April 2017, Pages 442-449
نویسندگان
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