کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5512004 | 1540217 | 2017 | 7 صفحه PDF | دانلود رایگان |

We present a facile synthesis of bovine serum albumin (BSA) conjugated low-dimensional ZnS nanocrystals. The experimental parameters such as effects of BSA concentration and precursor vol ratios of Zn:S on the formation of ZnS nanoparticles in BSA matrix were investigated. The ZnS crystalline sizes of 1.9, 1.8 and 1.6Â nm were obtained by using the BSA concentrations of 1Â ÃÂ 10â4, 5Â ÃÂ 10â4 and 10Â ÃÂ 10â4Â g/mL, respectively, with a fixed Zn:S vol ratio of 1:1. The ZnS samples prepared from 1:10 and 10:1 vol ratios of Zn:S at BSA concentration of 5Â ÃÂ 10â4Â g/mL shows the crystalline sizes of ZnS are 2.1 and 1.5Â nm, respectively. FTâIR analysis suggests that the prepared ZnS nanoparticles might be conjugated through the interactions of hydroxyl and amine groups present in BSA. We evaluate the cytotoxicity of the prepared ZnS nanoparticles, the THP-1 cells showed a good viability (>88%) for all the prepared ZnS samples. The plausible mechanism for the formation of ZnS-BSA composite has also been discussed.
Journal: International Journal of Biological Macromolecules - Volume 101, August 2017, Pages 729-735