کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5512004 1540217 2017 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Facile synthesis of bovine serum albumin conjugated low-dimensional ZnS nanocrystals
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Facile synthesis of bovine serum albumin conjugated low-dimensional ZnS nanocrystals
چکیده انگلیسی

We present a facile synthesis of bovine serum albumin (BSA) conjugated low-dimensional ZnS nanocrystals. The experimental parameters such as effects of BSA concentration and precursor vol ratios of Zn:S on the formation of ZnS nanoparticles in BSA matrix were investigated. The ZnS crystalline sizes of 1.9, 1.8 and 1.6 nm were obtained by using the BSA concentrations of 1 × 10−4, 5 × 10−4 and 10 × 10−4 g/mL, respectively, with a fixed Zn:S vol ratio of 1:1. The ZnS samples prepared from 1:10 and 10:1 vol ratios of Zn:S at BSA concentration of 5 × 10−4 g/mL shows the crystalline sizes of ZnS are 2.1 and 1.5 nm, respectively. FT−IR analysis suggests that the prepared ZnS nanoparticles might be conjugated through the interactions of hydroxyl and amine groups present in BSA. We evaluate the cytotoxicity of the prepared ZnS nanoparticles, the THP-1 cells showed a good viability (>88%) for all the prepared ZnS samples. The plausible mechanism for the formation of ZnS-BSA composite has also been discussed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Biological Macromolecules - Volume 101, August 2017, Pages 729-735
نویسندگان
, , , ,