Synthesis and anticancer activity of bile acid dendrimers with triazole as bridging unit through click chemistry

- Synthesis of new triazole based bile acid dendrimers via click chemistry.
- All the dendrimers were characterized by spectral and analytical data.
- All the dendrimers showed obvious cytotoxic activities against C6 glioma cells.
- Higher-generation dendrimers exhibit better anticancer activity than lower-generation dendrimers.

Triazole-based novel dendrimers with bile acid surface groups have been synthesized through click chemistry by divergent approach and characterized by spectral data. All the dendrimers exhibit excellent anticancer activity. Higher-generation dendrimers exhibit better anticancer activity than the lower-generation dendrimers.

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