کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5520060 1544560 2016 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Biocompatibility and safety of PLA and its copolymers
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیوتکنولوژی یا زیست‌فناوری
پیش نمایش صفحه اول مقاله
Biocompatibility and safety of PLA and its copolymers
چکیده انگلیسی

PLA and its copolymers are commonly used for a wide variety of applications. While they are considered to be biocompatible, side effects resulting from their implantation have been reported. The implantation of biomaterials always results in a foreign body reaction. Such a reaction has also been reported following PLA and its copolymers. This article reviews the process of inflammatory reaction that is to be expected following implantation of PLA, and it highlights specific cases in which the inflammatory reaction can result in safety concerns. The authors also review selected cases from different medical fields to demonstrate possible clinical side effects resulting from its use.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Advanced Drug Delivery Reviews - Volume 107, 15 December 2016, Pages 153-162
نویسندگان
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