ReviewFoundationCancer control potential of marine natural product scaffolds through inhibition of tumor cell migration and invasion

- Modern drug discovery efforts are leaning toward natural product-based scaffolds.
- Marine natural products exemplify novel resources for new drugs.
- Marine organisms offer architecturally complex and unique structural features.
- Several MNPs can effectively target cancer cell migration and invasion.

The marine environment is a reliable source for the discovery of novel treatment options for numerous diseases. Past research efforts toward the discovery of marine-derived anticancer agents have resulted in several commercially available marine-based drugs. The pharmaceutical value of anticancer drugs from marine natural products (MNPs) ranges from US$563 billion to US$5.69 trillion. In this review, we highlight several marine-derived entities with the potential for cancer control and prevention through the inhibition of crucial tumor cell motility and/or migration steps involved in subsequent cancer metastases. This report also covers the major hurdles typically faced by the MNPs research scientific community.

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