کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5539850 | 1553514 | 2017 | 17 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Ectonucleotidase and adenosine deaminase as inflammatory marker in dairy cows naturally infected by Dictyocaulus viviparus
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Ectonucleotidase and adenosine deaminase as inflammatory marker in dairy cows naturally infected by Dictyocaulus viviparus Ectonucleotidase and adenosine deaminase as inflammatory marker in dairy cows naturally infected by Dictyocaulus viviparus](/preview/png/5539850.png)
چکیده انگلیسی
The aim of this study was to evaluate the influence of dictyocaulosis (mild or severe) on enzymes of NTPDase, 5â²-nucleotidase, and adenosine deaminase (ADA) of dairy cows naturally infected by Dictyocaulus viviparus. Blood and faeces were collected from 22 dairy cows of the same farm to evaluate NTPDase (ATP and ADP substrate), 5â²-nucleotidase, and ADA activities on days 0 (pre-treatment) and 10 (post-treatment). Seric activities of NTPDase (ATP substrate), 5â²-nucleotidase, and ADA were lower (P < 0.05) in D. viviparus infected animals compared to uninfected cows. The number of D. viviparus larvae per gram of faeces varied among the animals, and they showed different degrees of severity according to respiratory clinical signs of the disease (cough and nasal discharge). Later, these cows were divided into two groups: those with mild (n = 10) and severe (n = 12) disease. Cows with severe disease showed higher NTPDase activity (ATP substrate) than those with mild disease (P â¤Â 0.05). The opposite occurred with NTPDase (ADP substrate), 5â²-nucleotidase, and ADA in cows with severe disease, that is, the enzymatic activity of these seric enzymes significantly decreased (P â¤Â 0.05) compared to animals with mild disease. Infected animals showed reduced NTPDase activity (ATP and ADP substrate) after treatment. No enzymatic changes were observed for 5â²-nucleotidase, and ADA pre- and post-treatment (P > 0.05). Based on these results, we conclude that dictyocaulosis alters NTPDase, 5â²-nucleotidase, and ADA activities of cow naturally infected by the parasite, in consequence the enzymes act as inflammatory markers.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Comparative Immunology, Microbiology and Infectious Diseases - Volume 51, April 2017, Pages 9-13
Journal: Comparative Immunology, Microbiology and Infectious Diseases - Volume 51, April 2017, Pages 9-13
نویسندگان
Aleksandro S. da Silva, Matheus D. Baldissera, Nathieli B. Bottari, Pedro H. Doleski, Guilherme M. Carmo, Claiton I. Schwertz, Neuber J. Lucca, Luan C. Henker, Manoela M. Piva, PatrÃcia Giacomin, Lenita M. Stefani, Daniela B.R. Leal, Gustavo Machado,