Serum C-reactive protein and ferritin concentrations in dogs undergoing leishmaniosis treatment

All dogs which totally recovered after treatment showed CRP and ferritin values within reference ranges. Most of dogs classified as having only partial clinical remission had CRP and ferritin within the reference range values despite the presence of other biochemical abnormalities such as hyperglobulinemia, hyperproteinemia, or proteinuria. On the other hand, most of dogs in the unresponsive group had increased CRP and ferritin. Although the study has limitations due to the variability in the protocols and time periods of treatments, it can be concluded that CRP and ferritin concentrations within the reference ranges are usually associated with the absence of clinical signs and adequate response to treatment and increased CRP and/or ferritin values could reflect a lack of appropriate response to treatment.