کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5554994 | 1559623 | 2017 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Isocoumarin derivatives from the endophytic fungus, Pestalotiopsis sp.
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
داروشناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Isocoumarin derivatives from the endophytic fungus, Pestalotiopsis sp. Isocoumarin derivatives from the endophytic fungus, Pestalotiopsis sp.](/preview/png/5554994.png)
چکیده انگلیسی
Five new isocoumarin derivatives, pestalactone A-C (1-3) and pestapyrone D-E (4-5), together with two known compounds (6-7) were isolated from the solid cultures of the endophytic fungus Pestalotiopsis sp. obtained from Photinia frasery. Their structures were mainly determined by extensive spectroscopic analysis, Mo2(OCOCH3)4-induced electronic circular dichroism (ECD), and ECD calculation. Compounds 1 and 2 were rare isocoumarin derivatives and derived from distinctive polyketide pathways. Compound 3 exhibited potent antifungal activity against Candida glabrata (ATCC 90030) with an MIC50 value of 3.49 ± 0.21 μg/mL.
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 122, October 2017, Pages 115-118
Journal: Fitoterapia - Volume 122, October 2017, Pages 115-118
نویسندگان
Ren-Yu Song, Xiao-Bing Wang, Guo-Ping Yin, Rui-Huan Liu, Ling-Yi Kong, Ming-Hua Yang,