کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5555078 | 1559630 | 2016 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Two new steroidal glycosides with unique structural feature of 14α-hydroxy-5β-steroids from Reineckia carnea
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
داروشناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Two new steroidal glycosides with unique structural feature of 14α-hydroxy-5β-steroids from Reineckia carnea Two new steroidal glycosides with unique structural feature of 14α-hydroxy-5β-steroids from Reineckia carnea](/preview/png/5555078.png)
چکیده انگلیسی
Two new steroidal glycosides (1-2) were isolated from the roots of Reineckia carnea, together with three known compounds (3-5). Their structures were determined on the basis of chemical methods and spectral data. Compounds 1-2 were the unique steroidal glycosides possessing structural feature of 14α-hydroxy-5β-steroids, and compounds 4-5 were isolated from R. carnea for the first time. The isolated compounds (1-5) were tested in vitro for their cytotoxic activities against the A549, HepG 2 and Caski cancer cell lines. Among them, the compounds 2 and 3 showed cytotoxicity against Caski cancer cell line with IC50 values of 34.4 and 3.7 μM, respectively.
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 115, December 2016, Pages 19-23
Journal: Fitoterapia - Volume 115, December 2016, Pages 19-23
نویسندگان
Ju-Yan Zheng, Qian Wang, Zhao-Xia L\iu, Cheng-Xiong Liu, Zhi-Yong Guo, Hong-Qi Zhang, Hai-Bo He, Xuan Tu, Kun Zou,