New insights into the ameliorative effects of ferulic acid in pathophysiological conditions

- Pharmacokinetic and pharmacodynamic properties of ferulic acid.
- Effect of ferulic acid on inflammation and apoptosis.
- Effect of ferulic acid in different pathophysiological conditions.
- Effect of ferulic acid on different signaling molecules.

Ferulic acid, a natural phytochemical has gained importance as a potential therapeutic agent by virtue of its easy commercial availability, low cost and minimal side-effects. It is a derivative of curcumin and possesses the necessary pharmacokinetic properties to be retained in the general circulation for several hours. The therapeutic effects of ferulic acid are mediated through its antioxidant and anti-inflammatory properties. It exhibits different biological activities such as anti-inflammatory, anti-apoptotic, anti-carcinogenic, anti-diabetic, hepatoprotective, cardioprotective, neuroprotective actions, etc. The current review addresses its therapeutic effects under different pathophysiological conditions (eg. cancer, cardiomyopathy, skin disorders, brain disorders, viral infections, diabetes etc.).