|کد مقاله||کد نشریه||سال انتشار||مقاله انگلیسی||ترجمه فارسی||نسخه تمام متن|
|5565206||1563201||2017||7 صفحه PDF||سفارش دهید||دانلود رایگان|
- affron®, a natural extract from saffron (Crocus Sativus L.) improves mood without side effects after one month of treatment.
- Tension, depression, confusion and fatigue (POMS) diminished in the 28Â mg/day treated group.
- The increased vigor (POMS) at a 28Â mg/day dose.
- The 28Â mg/day treated group showed a decrease in stress and depression (DASS-21).
BackgroundIn recent years phytotherapy has been explored as a source for alternative treatments for mood disorders. One potential candidate is saffron (Crocus sativus L.), whose main bioactive components are crocins and safranal.ObjectivesThe aim of this study was to investigate the efficacy of affron®, a standardised stigmas extract from Crocus sativus L. for improving mood, stress, anxiety and sleep quality in healthy adults.MethodsIn this 3 arm study, 128 participants self-reporting low mood but not diagnosed with depression, were given affron® at 28Â mg/day, 22Â mg/day, or a placebo treatment in a randomized, double-blind, placebo-controlled trial for 4 weeks. Mood was measured at baseline and at the end of the study, using the POMS (primary outcome measure) and PANAS questionnaires, and the DASS-21 scale. Sleep was monitored using Sleep Quality Index (PSQI).ResultsAnalysis indicated a significant decrease in negative mood and symptoms related to stress and anxiety at a 28Â mg/day dose (with a significant difference between 28Â mg/day and placebo on the POMS Total Mood Disturbance scale, pÂ <Â 0.001, dÂ =Â â1.10), but no treatment effect at the 22Â mg/day dose.LimitationsThe main weaknesses of this investigation were found in the self-reporting nature of both the screening and the testing.Conclusionsaffron® increased mood, reduced anxiety and managed stress without side effects, offering a natural alternative to standard treatments.
Journal: Complementary Therapies in Medicine - Volume 33, August 2017, Pages 58-64