کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5573707 | 1565350 | 2014 | 19 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Dehydrated Amniotic Membrane Allograft for Treatment of Chronic Leg Ulcers in Patients With Multiple Comorbidities: A Case Series
ترجمه فارسی عنوان
آلوترفت غشای آمنیوتیک خشک برای درمان زخم های مزمن مزاج در بیماران مبتلا به کمخونی های متعدد: یک سری موارد
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کلمات کلیدی
آلوگرافت غشای آمنیوتیک، محصولات مبتنی بر بافت بیولوژیک، زخم پا، التیام زخم،
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
ارتوپدی، پزشکی ورزشی و توانبخشی
چکیده انگلیسی
Cellular and/or tissue-based products (CTPs) are emerging treatment options for chronic non-healing wounds. Dehydrated amniotic membrane allograft (DAMA) was used in 7 patients whose wounds had not responded adequately to standard and adjuvant therapies; four VLUs, 2 surgical wounds, and 1 DFU. Patients had multiple comorbidities, including 2 with autoimmune disorders (CREST syndrome and systemic lupus erythematosus). Patients received 3-8 applications of DAMA at weekly to biweekly intervals (average, 5.4 applications). Complete wound healing was observed in 6 of 7 patients during study period, with an average time to closure of 7.9 weeks. Closure was achieved in 3 of 7 patients after 3 DAMA applications. In the patient with CREST syndrome who did not completely close, DAMA reduced the area and volume by nearly 50% and later went on to closure. These cases suggest that DAMA is a viable option for recalcitrant DFUs, VLUs, and surgical wounds.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American College of Clinical Wound Specialists - Volume 6, Issue 3, December 2014, Pages 38-45
Journal: Journal of the American College of Clinical Wound Specialists - Volume 6, Issue 3, December 2014, Pages 38-45
نویسندگان
Stephen M. MD, FAPWCA,