Tauroursodeoxycholic Acid Attenuates Angiotensin II Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-deficient Mice by Inhibiting Endoplasmic Reticulum Stress

The results suggest that ER stress is involved in human and Ang II induced AAA formation in ApoE−/− mice. TUDCA attenuates Ang II induced AAA formation in ApoE−/− mice by inhibiting ER stress mediated apoptosis.