A sirtuin 1/MMP2 prognostic index for myocardial infarction in patients with advanced coronary artery disease

*SIRT1: sirtuin 1; MMP2: matrix metalloproteinase 2; AROS: Active regulator of SIRT1; IL-21: interleukin 21; mTOR: mammalian target of rapamycin; NF-kB: nuclear factor kappa-light-chain-enhancer of activated B cells; eNOS: endothelial nitric oxide synthase; PGC-1α: peroxisome proliferator-activated receptor gamma coactivator 1-alpha; FOXO 3: Forkhead box O3; ECM: extracellular matrix; VEGF: vascular endothelial growth factor; TNF-α: tumor necrosis factor alpha; CVD: cardiovascular disease; MI: myocardial infarction; LVEF: left ventricular ejection fraction.78