کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5605205 1576116 2017 27 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Under-representation of elderly and women in clinical trials
ترجمه فارسی عنوان
تحت بازنمایی سالمندان و زنان در آزمایشات بالینی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی
Compared to their younger counterparts, elderly have a higher incidence of disease-related morbidities, take more medicines and account for more adverse drug related events. Similarly, women present several differences in CVD pathophysiology, clinical manifestations and outcomes in comparison to their male counterparts. For these reasons, the results of RCTs obtained in younger men cannot be simply translated in elderly and women. Unfortunately, although international guidelines have been published to increase the enrolment of elderly and women, their recruitment is still insufficient. Thus, the inclusion of these subgroups in cardiovascular RCTs is a key aspect to acquire evidence-based knowledge in the understanding and management of CVDs in elderly and women.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Cardiology - Volume 232, 1 April 2017, Pages 216-221
نویسندگان
, , , , , ,