کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5613929 | 1578014 | 2017 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
What is the association between left ventricular diastolic dysfunction and 6-minute walk test in hypertensive patients?
ترجمه فارسی عنوان
ارتباط بین اختلال عملکرد دیاستولیک بطن چپ و آزمون پیاده روی 6 دقیقه در بیماران مبتلا به فشار خون بالا چیست؟
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کلمات کلیدی
اختلال عملکرد دیاستولیک، نارسایی قلبی، فشار خون، آزمایش شش دقیقه پیاده روی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
سیستم های درون ریز و اتونومیک
چکیده انگلیسی
Heart failure (HF) is a major health problem. Hypertension is an important cause of HF. Most hypertensive patients have some degree of left ventricular (LV) diastolic dysfunction. The 6-minute walk test (6MWT) provides objective data about the exercise tolerance. We aimed to find the association between the degree of LV diastolic dysfunction and the functional capacity assessed by 6MWT in hypertensive patients. The study included 200 asymptomatic hypertensive patients. All patients had undergone full history taking, complete clinical examination, electrocardiography, echocardiography for assessment of LV dimensions, systolic and diastolic dysfunction, and 6MWT. Patients were classified into two groups according to the presence or absence of LV diastolic dysfunction. Clinical and echocardiographic data were comparable between the two groups. Regarding 6MWT, at the end of the test, patients with diastolic dysfunction had significantly higher systolic (P = .0088) and diastolic (P = .019) blood pressure and higher Borg score for dyspnea (P < .00001). The distant walked and percentage of the distance to predicted value were significantly lower in patients with diastolic dysfunction (P = .0322 and .0002, respectively). Incidence of abnormal 6MWT was significantly higher in patients with diastolic dysfunction (P = .00041). Compared to patients with grades I and II, patients with grade III diastolic dysfunction had significantly higher Borg score (P = .013), lower distance walked (P = .039), and lower percentage of distance to predicted vale (P = .009). Independent predictors for abnormal 6MWT were as follows: E/E' â¥15 (P = .0022), E'/A' <1 (P = .0081), and deceleration time of E-wave <160 (P = .013). The presence of LV diastolic dysfunction in hypertensive patients has a bad effect on 6MWT. The degree of LV diastolic dysfunction was correlated with 6MWT results. It may be important to investigate LV diastolic function in asymptomatic hypertensive patients.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of the American Society of Hypertension - Volume 11, Issue 3, March 2017, Pages 158-164
Journal: Journal of the American Society of Hypertension - Volume 11, Issue 3, March 2017, Pages 158-164
نویسندگان
El-Sayed M. MD, Mohammad M. MD, Marwa M. MD,