Metabolic Modulation by Medium-Chain Triglycerides Reduces Oxidative Stress and Ameliorates CD36-Mediated Cardiac Remodeling in Spontaneously Hypertensive Rat in the Initial and Established Stages of Hypertrophy

- Medium-chain triglycerides stimulated fatty acid metabolism in SHR.
- Metabolic modulation prevented cardiac remodeling.
- Prevention of cardiac remodeling, possibly by reduction of oxidative stress and maintenance of energy level.
- Prevention of cardiac remodeling is independent from blood pressure.