کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5614736 | 1405939 | 2017 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Rationale, design, and baseline characteristics of a study to evaluate the effect of febuxostat in preventing cerebral, cardiovascular, and renal events in patients with hyperuricemia
ترجمه فارسی عنوان
مبانی، طراحی و ویژگیهای ابتدایی یک مطالعه برای ارزیابی اثر فیبوکستات در جلوگیری از حوادث مغزی، قلب و عروق و کلیوی در بیماران مبتلا به هیپواریسمی
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
چکیده انگلیسی
This study is a prospective randomized open-label blinded endpoint study. Patient enrolment was started in November 2013 and was completed in October 2014. The patients will be followed for at least 3 years. The primary endpoint is a composite of cerebral, cardiovascular, and renal events, and all deaths including death due to cerebral, cardiovascular, and renal disease, new or recurring cerebrovascular disease, new or recurring non-fatal coronary artery disease, cardiac failure requiring hospitalization, arteriosclerotic disease requiring treatment, renal impairment, new atrial fibrillation, and all deaths other than cerebral or cardiovascular or renal disease. These events will be independently evaluated by the Event Assessment Committee under blinded information regarding the treatment group. The study was registered at ClinicalTrials.gov with the identifier NCT01984749.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Cardiology - Volume 69, Issue 1, January 2017, Pages 169-175
Journal: Journal of Cardiology - Volume 69, Issue 1, January 2017, Pages 169-175
نویسندگان
Sunao MD, PhD, FJCC, Kunihiko MD, PhD, Hisao MD, PhD, FJCC, Hideaki MD, PhD, Shinya MD, Takahiro MD, PhD, FJCC, Naoto MD, PhD, Naoki MD, Eiichi MD, Kazuaki MD, PhD, Masahiro MD, PhD, Hirokazu MD, Yutaka MD, Hisao MD, PhD, Ichiro MD, PhD, FJCC, Masako MD,