کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5620552 | 1579034 | 2017 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Valor diagnóstico y pronóstico del mapeo de T1 mediante RMC de los pacientes con insuficiencia cardiaca y fracción de eyección conservada
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کلمات کلیدی
RMCVECMOLLIDisfunción diastólica - اختلال در دیاستولیکDiastolic dysfunction - اختلال عملکرد دیاستولیکCardiac magnetic resonance - انتقال انرژی رزونانس فلورسانسresonancia magnética cardiaca - رزونانس مغناطیسی قلبHeart failure with preserved ejection fraction - نارسایی قلب با کسر خروجی حفظ شدهT1 mapping - نقشه برداری T1
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Heart failure with preserved ejection fraction (HFpEF) presents a major challenge in modern cardiology. Although this syndrome is of increasing prevalence and is associated with unfavorable outcomes, treatment trials have failed to establish effective therapies. Currently, solutions to this dilemma are being investigated, including categorizing and characterizing patients more diversely to individualize treatment. In this regard, new imaging techniques might provide important information. Diastolic dysfunction is a diagnostic and pathophysiological cornerstone in HFpEF and is believed to be caused by systemic inflammation with the development of interstitial myocardial fibrosis and myocardial stiffening. Cardiac magnetic resonance (CMR) T1-mapping is a novel tool, which allows noninvasive quantification of the extracellular space and diffuse myocardial fibrosis. This review provides an overview of the potential of myocardial tissue characterization with CMR T1 mapping in HFpEF patients, outlining its diagnostic and prognostic implications and discussing future directions. We conclude that CMR T1 mapping is potentially an effective tool for patient characterization in large-scale epidemiological, diagnostic, and therapeutic HFpEF trials beyond traditional imaging parameters.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Revista Española de CardiologÃa - Volume 70, Issue 10, October 2017, Pages 848-855
Journal: Revista Española de CardiologÃa - Volume 70, Issue 10, October 2017, Pages 848-855
نویسندگان
Karl-Philipp Rommel, Christian Lücke, Philipp Lurz,