The role of clotting factor IX in the development of atherosclerosis

- The severe deficiency of FIX did not protect the animals from the development of atherosclerotic plaques in the aortic areas evaluated after periods of 8 and 22 weeks.
- In the qualitative evaluation related to smooth muscle, and macrophages did not differ between.
- With the improvements in treatment for haemophilia and prolonged survival, atherosclerosis and cardiovascular disease would certainly be on the rise in these patients.