کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5632047 1406525 2017 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Is one trial enough for repeated testing? Same-day assessments of walking, mobility and fine hand use in people with myotonic dystrophy type 1
ترجمه فارسی عنوان
یک آزمون برای آزمایش مکرر کافی است؟ ارزیابی های روزانه در راه رفتن، تحرک و استفاده خوب دست در افراد مبتلا به نوع دیستروفی میوتونی 1
کلمات کلیدی
دیستروفی میوتونی معیارهای نتیجه، قابلیت اطمینان، تعداد آزمایشات، اقدامات تکراری، توانبخشی،
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب تکاملی
چکیده انگلیسی


- Physical function assessments are essential in myotonic dystrophy type 1 (DM1).
- Performance-based measures of walking, mobility and fine hand use are commonly used.
- Number of trials needed at a same-day test occasion was explored in 70 adults with DM1.
- Depending on test, one or two trials seem sufficient for a same-day assessment.
- People with severe muscular impairments had difficulties to perform repeated trials.

Performance-based assessments of physical function are essential in people with myotonic dystrophy type 1 (DM1) to monitor disease progression and evaluate interventions. Commonly used are the six-minute walk test, the 10 m-walk test, the timed up-and-go test, the timed-stands test, grip strength tests and the nine-hole peg test. The number of trials needed on a same-day test occasion and whether the first, best or average of trials should be reported as result is unknown. Thus, the aim was to describe and explore differences between trials in these measures of walking, mobility and fine hand use in 70 adults with DM1. Three trials were performed for each test except for the six-minute walk test where two trials were allowed. There were statistical significant differences over trials in all tests except for the 10 m-walk test and grip strength tests. Pair-wise comparisons showed that the second and third trials were in general better than the first, although effect sizes were small. At which trial the individuals performed their best differed between individuals and tests. People with severe muscular impairment had difficulties to perform repeated trials. Intraclass correlation coefficients were all high in analyses exploring how to report results. The conclusion and clinical implication is that, for a same-day test occasion, one trial is sufficient for the 10 m-walk test and grip strength tests, and that repeated trials should be allowed in the timed up-and-go test, timed-stands test and nine-hole peg tests. We recommend that two trials are performed for these latter tests as such a protocol could accommodate people with various levels of impairments and physical limitations.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuromuscular Disorders - Volume 27, Issue 2, February 2017, Pages 153-158
نویسندگان
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