Antibiotic Resistance in Severe Orofacial Infections

A serious increase in clindamycin and erythromycin resistance was found for S viridans and Staphylococcus species. Age, surgical history, and number of cultured aerobes showed a statistically meaningful correlation to antibiotic resistance. Presence of antibiotic resistance failed to show statistically relevant correlations to prolongation of hospital stay. Rather, the need for change in antibiotic regimen, the need for re-drainage, and increased serum urea nitrogen level were associated with longer hospital stay.