کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5644026 1406966 2017 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Micro- and macro-metastasis in the axillary lymph node: A review
ترجمه فارسی عنوان
میکرو و ماکرو متاستاز در گره لنفاوی زیر بغل: بررسی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی دندانپزشکی، جراحی دهان و پزشکی
چکیده انگلیسی

Pathologists typically examine the sentinel lymph nodes excised from patients with invasive breast cancer more thoroughly than they have historically those from axillary lymph node clearance specimens. This, it is thought, increases the chances of detecting small metastatic foci (i.e. macrometastases (>2 mm), micrometastases (0.2-2 mm), or isolated tumour cell clusters (<0.2 mm or <200 cancer cells in one section)). However, the clinical significance of these small metastatic deposits remains unclear. Although an increasing nodal burden is known to proportionally decrease patient survival, the American College of Surgeons Oncology Group (ACOSOG) Z0011 trial has, at the least, raised questions as to how best to manage nodal metastasis in early invasive breast cancer. These issues, and a brief overview of the biology of metastatic spread are presented in this review.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Surgeon - Volume 15, Issue 2, April 2017, Pages 76-82
نویسندگان
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