کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5653852 1589105 2017 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Endotracheal Intubation after Acute Drug Overdoses: Incidence, Complications, and Risk Factors
ترجمه فارسی عنوان
لوله گذاری تراشه پس از مصرف بیش از حد مواد مخدر: بروز، عوارض و عوامل خطر
کلمات کلیدی
بیش از حد، لوله گذاری عوامل خطر،
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی طب اورژانس
چکیده انگلیسی

BackgroundDrug overdose is the leading cause of injury-related fatality in the United States, and respiratory failure remains a major source of morbidity and mortality.ObjectivesWe aimed to identify the incidence and risk factors for endotracheal intubation after acute drug overdose.MethodsThis secondary data analysis was performed on a 5-year prospective cohort at two urban tertiary-care hospitals. The present study analyzed adult patients with suspected acute drug overdose to derive independent clinical predictors of endotracheal intubation.ResultsWe analyzed 2497 patients with acute drug overdose, of whom 87 (3.5%) underwent endotracheal intubation. Independent clinical risk factors for endotracheal intubation were: younger age (odds ratio [OR] 0.97, 95% confidence interval [CI] 0.96-0.98), and history of obstructive lung disease (OR 6.6, 95% CI 3.5-12.3); however, heart failure had no association. Patients with obstructive lung disease had significantly more hypercapnia (mean difference 6.8 mm Hg, 95% CI 2.3-11.3) and a higher degree of acidemia (mean pH difference 0.04, 95% CI 0.01-0.07) than patients without obstructive lung disease. Lack of rapid sequence sedative/paralytic was associated with in-hospital fatality. Early complications of endotracheal intubation itself included desaturation (3.4%) and bradycardia (1%).ConclusionsEndotracheal intubation was infrequently performed on patients with acute drug overdose, and complications were rare when performed. Risk factors associated with endotracheal intubation included younger age and prior obstructive lung disease.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The Journal of Emergency Medicine - Volume 52, Issue 1, January 2017, Pages 59-65
نویسندگان
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