کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5661651 1407538 2017 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Risk of low birth weight and micronutrient deficiencies in neonates from mothers after gastric bypass: a case control study
ترجمه فارسی عنوان
خطر کم وزن هنگام تولد و کمبود مواد مغذی در نوزادان مادران پس از معاینه معده: یک مطالعه مورد شاهدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری‌های گوارشی
چکیده انگلیسی

BackgroundAn increased risk of small-for-gestational-age infants after maternal bariatric surgery has been shown. The risk of micronutrients deficiencies in these neonates is unclear.ObjectiveTo screen for micronutrients deficiencies in newborns of mothers with gastric bypass.SettingsUniversity hospital in Angers, France.MethodsThis study compared the clinical and cord blood biological characteristics of 56 newborns of mothers with prior Roux-en-Y gastric bypass (RYGB) and 56 newborns of nonobese healthy mothers after normal pregnancy (controls), followed between January 3, 2008 and October 31, 2012. Cord blood micronutrients concentrations from controls were used for establishing normative data. After RYGB, the women took daily micronutrients supplements.ResultsRYGB mothers lost 18.1±6.3 kg/m2 of body mass index (BMI) in the 11-69 months between surgery and pregnancy onset (percentage of excess weight loss 79±20%), reaching BMI of 30.1±6.0 kg/m2 compared with 22.3±4.0 kg/m2 in the controls (P<.05). Neonates born to RYGB mothers were small-for-gestational-age in 23% of cases versus 3.6% in the control group (P<.01). A higher percentage of RYGB neonates had cord blood concentrations below the 2.5 percentile for calcium (19% versus 2%), zinc (13% versus 3%,), iron (19% versus 2%), and vitamin A (13% versus 3%), and over the 97.5 percentile for magnesium (13% versus 3%), vitamin E (16% versus 3%), 25-hydroxy-vitamin D (13% versus 2%), and vitamin B12 (14% versus 2%) (P<.05 for all comparisons).ConclusionNeonates from RYGB mothers showed cord blood micronutrient differences compared with neonates from healthy mothers. The comparison with neonates from morbidly obese women is still to be done.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Surgery for Obesity and Related Diseases - Volume 13, Issue 8, August 2017, Pages 1384-1391
نویسندگان
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