Differential effects of nitric oxide and cyclo-oxygenase inhibition on the diameter of porcine retinal vessels with different caliber during hypoxia ex vivo

The mechanisms underlying hypoxia induced dilatation differ among smaller porcine retinal vessels with different caliber ex vivo. This may reflect differences in the responses of retinal vessels to changes in metabolism, and may point to possible targets for pharmacological intervention on the diameter of retinal vessels with different caliber in vivo.