کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5717117 1411182 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
El nuevo reto en oncología: la secuenciación NGS y su aplicación a la medicina de precisión
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
پیش نمایش صفحه اول مقاله
El nuevo reto en oncología: la secuenciación NGS y su aplicación a la medicina de precisión
چکیده انگلیسی
Precision Medicine is an emerging approach for the diagnosis, treatment and prognosis of genetic diseases that enables clinicians to more accurately predict which treatment strategy will be optimal in a patient. The aim of Precision Medicine in Oncology is to integrate clinical, histological, and molecular data in order to obtain a deeper knowledge about the biology and genetics of an individual's tumour. Over the last few years, the implementation of new NGS (Next Generation Sequencing) technologies into clinical practice has been essential. There is a wide variety of NGS techniques that can be used in this context. The correct interpretation of molecular changes detected by these techniques is paramount for their appropriate use. In this review, a discussion is presented on the main NGS sequencing technologies that can be used to improve the diagnosis, prognosis, and treatment of oncology patients.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Anales de Pediatría - Volume 85, Issue 5, November 2016, Pages 273.e1-273.e7
نویسندگان
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