ReviewAutologous fat transplantation for breast reconstruction: A literature review

- Autologous fat transplantation does not compromise oncological outcomes and minimizes discomfort to the patients.
- The ASCs (adipose-derived stem cells) into the fat graft allow the regeneration of tissue after breast reconstruction.
- The role of lipofilling could be more significant with the findings of experimental research on tissue engineering and ASCs.

IntroductionThe use of autologous fat transplantation to correct volume and contour defects, scars, and asymmetry after breast cancer surgery has increased over the past 20 years. Many developments and refinements in this technique have taken place in recent years, and several studies of the safety of lipofilling in the breast have been published.Presentation of caseWe performed a literature review of this technique, highlighting the crucial role of lipofilling in breast cancer reconstruction.DiscussionThe efficacy of the fat graft transplantation depends on the experience and the technique used by the surgeon. The ASCs (adipose-derived stem cells) contained in the fat graft has proven to be crucial for breast reconstruction by mean the regeneration of tissue, through the chemotactic, paracrine, and immunomodulatory activities and their in situ differentiation.ConclusionThe role of lipofilling for breast reconstruction could be more significant with the application of the findings of experimental research on tissue engineering and ASCs.