کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5732698 | 1612077 | 2017 | 4 صفحه PDF | دانلود رایگان |

- IgG4-RM is exceedingly rare with only ten reported cases in the literatreu.
- Diagnosis of IgG4-RM is based exclusively on histological analysis.
- It is a benign chronic inflammatory process that can be treated sufficiently with excision or steroid.
- Extensive whole body imaging is generally not recommended unless the patient is symptomatic.
IntroductionIgG4-related mastitis (IgG4-RM) is exceedingly rare with only ten cases reported in the literature to date. Organs that are affected with IgG4-related disease (IgG4-RD) all share the same histopathological hallmarks consisting of dense lymphocytic infiltration, storiform fibrosis and obliterative phlebitis.Presentation of caseThis case report highlights a case of IgG4-RM found incidentally in a 52-year-old woman during a routine breast screen and it explores the current literature about IgG4-RM and IgG4-RD.DiscussionIgG4-RM and IgG4-RD, in general, is a new entity in the field of medicine and its aetiology is not well understood. In the literature, IgG4-RM often presents as a painless palpable breast lump in isolation or with other systemic manifestations. IgG4-RM is considered benign and has excellent prognosis post-conservative treatment with steroid or surgical excision.ConclusionIgG4-RM is diagnosed exclusively on histological analysis. It is hard to distinguish IgG4-RD from malignant breast lesions purely on clinical examination and imaging studies. Increasing awareness of this condition among clinicians will assist them in managing patients better. Extensive whole body imaging is not recommended unless symptomatic.
Journal: International Journal of Surgery Case Reports - Volume 37, 2017, Pages 169-172