کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5732806 1612075 2017 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Case ReportFree disease long-term survival in primary thoracic spine leiomyosarcoma after total en bloc spondylectomy: A case report
ترجمه فارسی عنوان
بیماری گزارش یک بیماری بیهوشی طولانی مدت در لیومیوسارکومی قفسه سینه اولیه پس از اسپوندیکتومی کامل ان بلوک: گزارش مورد
کلمات کلیدی
گزارش مورد، لیومیوسارکوم، ستون فقرات تناسلی، اسپوندیکتومی کامل ان بلوک،
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
چکیده انگلیسی


- Primary vertebral leiomyosarcoma in thoracic spine is extremely rare.
- Metastatic origin must be excluded.
- Wide surgical excision can result in local tumor control and long-term survival.

IntroductionTo describe an unusual primary vertebral leiomyosarcoma in thoracic spine.Presentation of caseAn isolated lesion of the T11 vertebra in a 62-year-old woman with no neurologic deficit is reported. Imaging findings indicated a nonspecific high-grade malignant lesion. TC-guided biopsy failed thus open incisional biopsy was needed. A diagnosis of low-intermediate mesenchymal sarcoma was made. A total en bloc spondylectomy of T11 was performed with three-column reconstruction. The histology and immunostaining showed the appearance of leiomyosarcoma. After diagnosis, post-operative radiation therapy was performed. Metastatic lesion was ruled out by CT scans of the chest, abdomen and pelvis, in addition to total body radionuclide scanning and 18-F-FDG-PET. After five years of follow-up, no signs of local recurrence, metastasis or distant lesions suggesting a primary lesion were observed.DiscussionVertebral primary leiomyosarcoma is exceedingly rare. Primary vertebral leiomyosarcoma diagnosis must be performed when the metastatic origin is excluded. For the treatment of primary tumors, total en bloc spondylectomy (TES) is the technique of choice to achieve marginal or wide tumor resection, decrease the risk of local recurrence and remote lesions and increase survival.ConclusionsA well-planned pre-operative study and a wide surgical excision can result in local tumor control and long-term survival. This case presents the longest disease-free survival period of a primary leiomyosarcoma in spinal location after total en bloc spondylectomy.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Surgery Case Reports - Volume 39, 2017, Pages 332-338
نویسندگان
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