کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5733304 1612085 2016 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Case reportEndoscopic resection of a periampullary gangliocytic paraganglioma of the duodenum: A case report
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
پیش نمایش صفحه اول مقاله
Case reportEndoscopic resection of a periampullary gangliocytic paraganglioma of the duodenum: A case report
چکیده انگلیسی


- The gangliocytic paraganglioma was resected endoscopically.
- Immunohistochemical examination reveal S100, synaptophysin and VIP expression.

IntroductionThe gangliocytic paraganglioma (GP) is an extremely rare neuroendocrine tumour originating from the second part of the duodenum. Generally GP shows benign clinical behaviour. The GP is typically characterized by consisting of three tumour components: the epithelioid, the spindle-shaped and the ganglion-like cells.Presentation of caseWe present a female patient at the age of 65, who underwent a routine gastroscopy due to known gastro-oesophageal reflux. Accidentally a 2 × 1,5 cm sized mass of unknown entity was revealed in the duodenum. The magnet resonance tomography neither detected distant metastasis nor any local lymphadenopathy. After endosonographically guided punctures of the submucosal mass, a malignant tumour could not be diagnosed thus the decision to perform an endoscopical resection was made and successfully conducted. Immunohistochemical examination revealed a total resected GP.DiscussionIn literature malignant transformation with distant metastasis and local recurrences has been described. Furthermore the clinical manifestation and location varies. The GP has often been misdiagnosed as a neuroendocrine tumour (NET) G1.ConclusionDue to published cases of metastasising GPs, we recommend a long term follow-up. In a non-metastatic stage the endoscopic resection should be the therapy of choice in order to prevent unnecessary major surgical interventions. In this case report we will discuss the clinical appearance, behaviour and differential diagnosis of GP.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Surgery Case Reports - Volume 29, 2016, Pages 39-43
نویسندگان
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