کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5733895 1612525 2017 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Regulation of myocardial stromal cell-derived factor 1α/CXCL12 by tumor necrosis factor signaling
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
پیش نمایش صفحه اول مقاله
Regulation of myocardial stromal cell-derived factor 1α/CXCL12 by tumor necrosis factor signaling
چکیده انگلیسی
Our study represents the initial evidence showing that TNF plays an inhibitory role in modulating myocardial SDF-1 production and blockade of TNF signaling by ablation of TNFR1 and TNFR2 genes increased SDF-1 expression in the heart. These data expand on TNF signaling-initiated mechanisms in myocardium, which may lend a more complete understanding of SDF-1 and TNFR-derived actions in hopes of advancing ischemic heart injury treatments.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Surgical Research - Volume 207, January 2017, Pages 155-163
نویسندگان
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