In vitro and in silico investigations of the binding interactions between chlorophenols and trypsin

- Binding interactions of five chlorophenols with trypsin were investigated.
- The number of chlorine atoms of chlorophenols partly affected the binding ability of them to trypsin.
- Noncovalent interactions stabilized the trypsin-chlorophenols complexes.
- There was the one main binding site of trypsin for chlorophenols.