Sequestration of total and methyl mercury in different subcellular pools in marine caged fish

► This is the first study on the subcellular fate of mercury in marine farmed fish. ► Metallothionein-like protein fraction had the highest degree of methylation. ► Mercury was predominantly bound with the cellular debris fraction. ► Only a small % of Hg was bound with metal-sensitive fraction. ► Subcellular study shred lights on the Hg detoxification and its bioavailability.